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Ask Dr. Warren M.D., Ph.D. how to increase metabolism.

Volume 1 No. 5 |

Ask Dr. Warren MD, PhD. Q&A 4

This email series is dedicated to helping people understand some of the techniques and strategies I use to help people stay healthy, avoid illnesses and get the most out of every dollar they spend on their health.


Can Mitochondria Dysfunction affect weight loss and metabolism?



Yes. In fact, many people that get older and say that their metabolism has slowed are right. The real question is why has their metabolism slowed?


My answer is that their metabolism has slowed because of mitochondria dysfunction. A slower metabolism makes it a lot more difficult than it should be to lose weight. I will teach you a simple trick I use called “Mitochondria-Targeted Supplements” to keep your increase metabolism and get it working optimally.

Let me start by explaining to you the five main ways that mitochondria dysfunction can affect weight loss and metabolism, they include:

  1. Reduced Energy Production: Mitochondrial dysfunction leads to impaired ATP production, resulting in decreased energy availability for cellular processes, including metabolism. This can contribute to fatigue, reduced physical activity, and a decreased ability to burn calories efficiently.

  2. Altered Metabolic Rate: Mitochondria play a central role in metabolism by regulating the breakdown of nutrients, such as carbohydrates, fats, and proteins, to generate energy. Dysfunction in mitochondria can disrupt metabolic pathways, leading to a sluggish metabolic rate and impaired energy expenditure, which may contribute to weight gain or difficulty in losing weight.

  3. Increased Oxidative Stress: Dysfunctional mitochondria produce higher levels of reactive oxygen species (ROS), which are harmful byproducts of cellular metabolism. Excessive ROS can damage cellular components, including DNA, proteins, and lipids, and contribute to inflammation and metabolic dysfunction, which may impair weight loss efforts.

  4. Impaired Lipid Metabolism: Mitochondria are involved in the oxidation of fatty acids for energy production. Dysfunction in mitochondrial fatty acid oxidation pathways can lead to the accumulation of lipids in tissues, insulin resistance, and metabolic syndrome, which are associated with obesity and difficulty in losing weight.

  5. Disrupted Hormone Regulation: Mitochondria play a role in the synthesis and regulation of various hormones involved in metabolism, including insulin and thyroid hormones. Dysfunction in mitochondrial function can disrupt hormone signaling pathways, leading to metabolic imbalances that affect weight regulation.


Metabolism+ bottle and tablets

My solution to help people to increase metabolism and keep it functioning optimally is through the use of mitochondria-targeted supplements.

My mitochondria-targeted supplement of choice for Metabolism and Weight loss is Metabolism+. Metabolism+ is a combination of Methylene Blue, Green Tea, Guarana and L-Theanine. I have my weight loss clients start with two to four tablets each morning. I have them use Metabolism+ along with any other weight loss medication like GLP-1 (Semaglutide, Tirzepatide), Metformin, etc. Regardless of their approach to weight loss I believe using Metabolism + tablets are beneficial as they target the health of the mitochondria. My bottom line on this front is that optimum metabolism starts by eliminating mitochondria dysfunction. I make sure this happens by providing targeted nutrients like those in Metabolism+. Give this approach a try, I am sure you will see better results. Yours in Health.

Steven Warren, MD, PhD


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